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Study of Co-Infections in the Female Genital Tract Uncovers New Molecular Mechanism for How Pathogens Evade the Immune System

“Our study is the first report to show molecular synergisms between bacteria, endosymbiont virus and protozoan parasite evading the human host – both with clinical association and experimental proof of causality,” said Raina Fichorova, MD, PhD, of the Brigham’s Department of Obstetrics and Gynecology. “It addresses the most common and devastating infections of the female reproductive tract, including protozoan (trichomonas), viral (HPV and herpes simplex virus), and bacterial (bacterial vaginosis pathobionts key to mucosal dysbiosis). Our paper is also the first to implicate galectins in viral-protozoan-bacterial-host interaction in the female genital tract.”

Read more in Frontiers in Cellular and Infection Microbiology 

Source: Brigham Clinical and Research News

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